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    About Fabry

    Disease Overview
    Effects & Progression
    Inheritance
    Variants & Types
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    Treatment
    Genetics

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  • About Galafold® (migalastat)
    > Taking Galafold

    You can decide how Galafold
    fits into your routine

    Veronica, living with Fabry
  • Treatment Options
  • Is Galafold Right for Me?
  • Taking Galafold
  • When to Take
    How to Take

    You can decide how Galafold fits into your routine

    Every other day is Galafold day.

    Galafold is taken every other day at the same time of day, and building Galafold into your routine can make it easier to remember.

    You pick a pill time that’s convenient for you.

    Because Galafold needs to be taken at the same time of day on an empty stomach, pick a time that works best for you and your eating schedule. The time doesn’t matter, as long as you are consistent.

    If you miss a dose of Galafold, take the missed dose of Galafold within 12 hours of your normal schedule. If more than 12 hours have passed, do not make up the missed dose. You should resume taking Galafold at your next scheduled day and time following your original every-other-day dosing schedule.

    Watch Alex’s full story
    Alex Patient Ambassador | Smiling

    “I put my Galafold package right next to my toothbrush. I see it at night as I am about to go to bed as I am brushing my teeth.” – Alex, on his Galafold routine.
    Watch his full story >

    Galafold must be taken on an empty stomach.

    Do not eat food, or take or drink any product that contains caffeine at least 2 hours before and 2 hours after taking Galafold to give a minimum 4 hour fast. You can drink the following beverages during this time when you cannot eat:

    • Water
      Plain, flavored, or sweetened
    • Fruit juices without pulp
    • Caffeine-free carbonated beverages
    Pill

    Packaging designed to help you take Galafold on schedule.

    When life gets hectic, it can be hard to remember pill time—especially if Galafold is a new step in your routine. That’s why each Galafold pack is made to help you keep track.

    Watch Joyce’s full story
    Joyce Patient Ambassador | Close-up

    “When I start a new package of Galafold, I like to write the day of the week above the capsule. I keep the package by my easy chair and it has become a habit to check it as the last thing I do before bed.” – Joyce, on her Galafold tracking.
    Watch her full story >

    Learn how to remove and take Galafold with this step-by-step video:

    Expand to read the step-by-step guide.

    How to remove a capsule

    How to Take Galafold | Remove a Capsule | Lift

    1 LIFT

    Remove the adhesive seal holding the cover. Lift the cover of your GALAFOLD carton.

    How to Take Galafold | Remove a Capsule | Press

    2 PRESS

    Press and hold down the purple tab with your thumb on the left side of the carton.

    How to Take Galafold | Remove a Capsule | Pull

    3 PULL

    Grasp the tab on the right side of the blister card where it says, “PULL OUT HERE” and pull out the folded blister card.

    How to Take Galafold | Remove a Capsule | Unfold

    4 UNFOLD

    Unfold the blister card.
    Tip: Press hard to allow the blister card to come out.

    Taking Galafold capsules

    How to Take Galafold | Taking Capsules | Record

    1 RECORD

    On your first day of taking GALAFOLD from a new blister card, record the date on the blister card next to “Starting date.”

    Tip: Take Galafold on an empty stomach. Do not eat food, or take or drink any product that contains caffeine at least 2 hours before and 2 hours after taking Galafold to give a minimum 4 hour fast.

    How to Take Galafold | Taking Capsules | Turn Over

    2 TURN OVER

    Locate the GALAFOLD capsule to remove for the dosing day. Turn the blister card over to show the back of the card.

    Bend the card as shown.
    Note: Bending the blister card helps raise the oval perforated cardboard.

    How to Take Galafold | Taking Capsules | Remove Cardboard

    3 REMOVE CARDBOARD

    Remove the oval perforated cardboard.
    Note: After removing the oval cardboard, the white backing of the foil may be present, which is ok.

    How to Take Galafold | Taking Capsules | Push Capsule

    4 PUSH CAPSULE

    Turn the blister card over to show the front of the card. Push the GALAFOLD capsule out.

    Tip: To avoid damaging the pill, press the bottom of the pill at an angle. Do not press the center of the capsule, as it may crush the pill. The pill should only be taken whole.

    How to Take Galafold | Taking Capsules | Next Day

    5 NEXT DAY

    On the next day, move to the perforated white cardboard circle on the top row. Press down on the white cardboard circle to remove it.

    Note: Removing this white cardboard circle will help you remember which day you do not take GALAFOLD. Take 1 GALAFOLD capsule every other day. Fold the blister card, and slide it back into the carton after each use.

    Change (alternate) each day between taking the GALAFOLD capsule and removing the perforated white cardboard circle until you reach Day 28.

    Galafold MyDay App | Phone Screen

    Keep track of your Galafold routine with the MyDay app.

    Available on the App Store and Google Play

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    Hear from others with Fabry disease

    When it comes to the Fabry community, everyone has a unique perspective to share.

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    IMPORTANT SAFETY INFORMATION AND INDICATION

    Before taking Galafold® (migalastat), tell your healthcare provider about all of your medical conditions, including if you:

    • have kidney problems.
    • are pregnant or plan to become pregnant. It is not known if Galafold will harm your unborn baby.

    IMPORTANT SAFETY INFORMATION AND INDICATION

    Before taking Galafold® (migalastat), tell your healthcare provider about all of your medical conditions, including if you:

    • have kidney problems.
    • are pregnant or plan to become pregnant. It is not known if Galafold will harm your unborn baby.
    • are breastfeeding or plan to breastfeed. Galafold may pass into breast milk. Talk to your healthcare provider
      about the best way to feed your baby if you take Galafold.

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines or supplements containing caffeine as these medicines or supplements may affect how Galafold works.

    How should I take Galafold?
    Do not eat food, or take or drink any product that contains caffeine at least 2 hours before and 2 hours after taking Galafold to give a minimum 4 hour fast.

    What are the possible side effects of Galafold?
    The most common side effects of Galafold include headache, stuffy or runny nose and sore throat, urinary tract infection, nausea, and fever.

    These are not all the possible side effects of Galafold. Call your healthcare provider for medical advice about side effects.

    What is Galafold?
    Galafold is a prescription medicine used to treat adults with Fabry disease who have a certain genetic change (variant) in the galactosidase alpha gene (GLA) that is responsive (amenable) to Galafold.

    It is not known if Galafold is safe and effective in children.

    You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Amicus Therapeutics at 1-877-4AMICUS.

    Please click here for Full Prescribing Information, including Patient Information and Instructions for Use.

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